Buy Danazol capsules online from a U.S. pharmacy

Product Name	Danazol (Danazol)
Dosage	50 mg, 100 mg, 200 mg
Active Ingredient	Danazol
Form	Oral Capsules
Description	Prescription androgenic medicine used in the USA for endometriosis, fibrocystic breast disease, and prevention of hereditary angioedema attacks.
How to Order	Prescription required in the United States (consult a licensed clinician or telehealth provider)

Danazol (danazol) is an established, FDA‑approved oral therapy in the United States. Unlike many symptomatic treatments, danazol modifies hormonal signaling to help manage specific conditions, including endometriosis, fibrocystic breast disease (also called benign breast pain or mastalgia), and the prevention of hereditary angioedema (HAE) attacks. In the U.S., Danazol is supplied as capsules in 50 mg, 100 mg, and 200 mg strengths. Because danazol is a prescription medication with important safety considerations, a U.S.-licensed clinician must review your medical history before it can be dispensed.

On this page, you’ll find comprehensive, U.S.-focused information about Danazol: approved indications, how it works, typical dosing regimens selected by clinicians, key warnings (especially regarding pregnancy), common and serious side effects, drug–drug interactions, and guidance on obtaining Danazol through legitimate U.S. pharmacy channels. We’ve also included practical tips on monitoring and follow-up so patients can navigate treatment confidently and safely.

Danazol price and affordability in the USA

Pricing for Danazol in the United States can vary based on dosage strength, quantity, manufacturer, and your pharmacy’s negotiated rates with insurers or discount programs. Danazol is available as a generic in the U.S., which often lowers out-of-pocket costs compared with legacy brand-name products. Patients with commercial insurance or Medicare Part D may have copays or coinsurance rather than paying the retail cash price. Those paying cash can often apply pharmacy discount cards or manufacturer-supported savings programs where eligible.

As a general rule, higher-strength capsules (e.g., 200 mg) cost more per capsule but may reduce the number of daily capsules required, while smaller strengths (50 mg or 100 mg) allow for more flexible dose adjustments. Your prescriber will choose a starting dose tailored to your diagnosis and clinical response, then typically titrate to the lowest effective dose to balance benefits with side-effect risk and cost.

To find current U.S. prices for Danazol near you, compare options among licensed pharmacies and check whether your health plan requires prior authorization for this therapy. If you’re using a mail-order pharmacy through your insurance, 90-day fills may provide additional savings and convenience. Always make sure you are purchasing from legitimate, U.S.-licensed pharmacies.

Where can I buy Danazol (danazol) in the USA?

If your U.S.-licensed clinician determines that Danazol is appropriate, it can be dispensed by any U.S.-licensed retail or mail-order pharmacy. Many patients prefer to use their local pharmacy for initial fills and a mail-order service for long-term maintenance therapy. Telehealth providers in the United States can also evaluate you and, if medically appropriate, send an electronic prescription to a licensed pharmacy for fulfillment.

Important: Danazol (danazol) is not an over-the-counter (OTC) product in the United States. A valid prescription from a U.S.-licensed prescriber is required. When you order online, ensure the pharmacy is properly licensed and will verify your prescription. Pharmacies that offer danazol without a prescription or bypass U.S. dispensing laws should be avoided for your safety.

Our platform connects U.S. consumers with reputable, licensed pharmacy partners. Ordering is straightforward: your clinician submits a prescription, the pharmacy verifies it, and then ships your medication discreetly to your U.S. address, subject to availability and local regulations.

Accessing care via telehealth

Telehealth can be a convenient option for many adults, especially for follow-up visits, side-effect check-ins, and dose adjustments. During the telehealth appointment, be prepared to discuss your medical history, all current medications and supplements, any history of liver disease, blood clots, or migraines with visual symptoms, and your pregnancy plans and contraception. Depending on your situation, baseline lab testing may be requested before treatment and at intervals thereafter.

What is Danazol (danazol)?

Danazol is a synthetic androgen with antiestrogenic and antigonadotropic activity. It suppresses the pituitary secretion of gonadotropins (LH and FSH), which can decrease estrogen production and ovulation in premenopausal women and reduce estrogen-mediated tissue growth. In hereditary angioedema, danazol raises levels of C1-esterase inhibitor, helping prevent swelling attacks.

In the U.S., danazol’s approved uses include:

• Management of endometriosis
• Treatment of fibrocystic breast disease (severe cyclic mastalgia and nodularity)
• Prophylaxis of hereditary angioedema (HAE) attacks

Because Danazol has androgenic properties and a distinct side-effect profile, it is typically reserved for patients in whom alternative therapies are not suitable or have not been effective, and it is used for the shortest duration necessary at the lowest effective dose.

How Danazol works (Mechanism of action)

Danazol modulates the hypothalamic–pituitary–gonadal axis. It exerts a negative feedback effect on pituitary gonadotropin release, decreasing LH and FSH secretion. The downstream reduction in ovarian steroidogenesis reduces estrogen levels and results in atrophy of endometrial implants, which can alleviate pelvic pain associated with endometriosis. In fibrocystic breast disease, reduced estrogenic stimulation can lessen breast pain and nodularity.

In hereditary angioedema, Danazol increases hepatic synthesis of C1-esterase inhibitor (C1-INH), elevating circulating levels and improving complement regulation. This reduces the frequency and severity of HAE attacks. The precise molecular mechanisms are complex and extend beyond a single receptor pathway; danazol exhibits weak androgen receptor agonism and minor progestational and glucocorticoid activity as well.

Danazol for endometriosis

Endometriosis is a chronic condition where endometrium-like tissue grows outside the uterus, commonly causing pelvic pain, dysmenorrhea, dyspareunia, and sometimes infertility. By suppressing gonadotropins and reducing estrogen levels, Danazol helps to induce a hypoestrogenic state, leading to regression of ectopic endometrial implants.

In the U.S., prescribers may consider Danazol when first-line options such as combined hormonal contraceptives, progestins, or GnRH modulators are contraindicated, not tolerated, or have failed to provide adequate relief. Benefits may become apparent within weeks, but full response often requires several months. Because of androgenic side effects and potential metabolic changes, clinicians generally aim for the lowest effective dose and limit duration of therapy according to the patient’s goals and response.

Clinician-selected dosing for endometriosis

Prescribers commonly initiate therapy in the 200–400 mg/day range divided into two doses, then titrate based on clinical response and tolerability. Typical U.S. treatment courses last 3 to 6 months. Your clinician may adjust the regimen to your symptoms, side effects, and laboratory results, using the minimal effective dose for the shortest time needed.

Danazol for fibrocystic breast disease

Fibrocystic breast disease is a benign condition characterized by diffuse breast pain, tenderness, and nodularity that commonly fluctuate with the menstrual cycle. For individuals with severe, refractory symptoms, Danazol may be considered after lifestyle changes (e.g., supportive bras, caffeine moderation), analgesics, and other hormonal approaches have not provided adequate relief.

In clinical practice, symptom improvement with danazol often correlates with reduced hormonal stimulation of breast tissue. Because androgenic effects can occur, prescribers start with the lowest dose likely to provide benefit and reassess frequently to minimize exposure.

Clinician-selected dosing for fibrocystic breast disease

Regimens are individualized. U.S. clinicians may start at 100–200 mg/day and adjust as needed. Short courses are common, and once symptoms have improved, your prescriber may taper or discontinue to determine the minimal dose and duration necessary to maintain relief.

Danazol for hereditary angioedema (HAE) prophylaxis

Hereditary angioedema is a rare genetic disorder marked by recurrent episodes of swelling in the skin, gastrointestinal tract, and airways. Prophylactic therapies aim to reduce the frequency and severity of attacks. Danazol is one of the long-standing oral options that increases C1-INH levels and can help prevent attacks in some patients.

Modern HAE management typically prioritizes targeted C1-INH replacement or other non-androgen prophylactic options due to improved safety profiles. However, danazol remains an option in select cases where newer therapies are not accessible or appropriate, provided careful monitoring is in place.

Clinician-selected dosing for HAE prophylaxis

Initial dosing sometimes begins at 200 mg two or three times daily, then is tapered to the lowest effective maintenance dose that prevents attacks (often 50–200 mg/day). Because of the potential for hepatic and metabolic adverse effects, ongoing monitoring and dose minimization are essential.

Who should not take Danazol?

Because of its hormonal effects and hepatic metabolism, Danazol is not appropriate for everyone. In the United States, common contraindications include:

• Pregnancy or potential pregnancy (Category X for teratogenic risk); a negative pregnancy test and reliable contraception are required prior to initiation and throughout treatment
• Breastfeeding
• Severe hepatic, renal, or cardiac disease
• Porphyria
• Androgen-dependent tumors or known/suspected malignancy influenced by androgens
• Undiagnosed vaginal bleeding
• History of thromboembolic events, significant clotting disorders, or severe hyperlipidemia without control

Before prescribing Danazol, your U.S.-licensed clinician will review your medical history, perform appropriate baseline lab tests (including liver function and lipids), and discuss contraception needs. If you develop signs of liver problems (e.g., persistent nausea, abdominal pain, yellowing of the skin or eyes, dark urine), severe headaches or visual changes, swelling of legs, chest pain, or shortness of breath, seek medical care immediately.

Pregnancy, contraception, and breastfeeding

Danazol must not be used during pregnancy because it may cause harm to a developing fetus, including virilization of a female fetus. For those who could become pregnant, a negative pregnancy test is typically required before starting therapy, and effective contraception should be used consistently during treatment and for a period after discontinuation as advised by your clinician. Notify your prescriber immediately if you become pregnant while taking Danazol.

Danazol passes into breast milk and may affect a nursing infant; therefore, breastfeeding is not recommended while using Danazol. Your clinician can discuss alternative therapies if you are pregnant or planning to become pregnant or are currently breastfeeding.

Danazol dosage and administration (U.S. guidance)

All dosing decisions must be made by a clinician who knows your medical history. The following information reflects common U.S. clinical practice patterns and is provided for educational purposes only:

• Endometriosis: Often initiated at 200–400 mg/day in two divided doses. Duration is commonly 3–6 months, with ongoing evaluation to use the lowest effective dose.
• Fibrocystic breast disease: Often 100–200 mg/day with individualized titration and limited duration.
• Hereditary angioedema prophylaxis: Some clinicians begin at 200 mg two to three times daily, then reduce gradually to a maintenance dose (e.g., 50–200 mg/day) that prevents attacks.

Capsules may be taken with food to reduce stomach upset if directed by your clinician. Take Danazol at the same times each day to maintain steady levels. Do not change your dose or stop therapy without consulting your prescriber.

Monitoring, labs, and follow-up

Because Danazol can affect the liver, lipid profile, and other systems, U.S. clinicians often recommend baseline and periodic tests, which may include:

• Liver function tests (ALT, AST, bilirubin)
• Lipid panel (HDL, LDL, triglycerides)
• Complete blood count (if clinically indicated)
• Pregnancy test before initiation (and as indicated)
• Clinical assessment for blood pressure, weight changes, acne, hirsutism, or voice changes

Your prescriber may adjust the dose or discontinue Danazol if lab abnormalities or concerning symptoms develop. The goal is to use the lowest effective dose for the shortest necessary time.

Potential side effects of Danazol

Like all prescription medicines, Danazol can cause side effects. Many are dose-dependent and reversible after dose reduction or discontinuation, though some may persist. Contact your clinician if side effects are severe or persist.

Common adverse effects

• Weight gain or fluid retention
• Acne, oily skin, or hair changes
• Hirsutism (increased body or facial hair)
• Hot flashes, flushing, or sweating
• Menstrual irregularities or amenorrhea
• Breast tenderness or decreased breast size
• Mood changes, nervousness, or fatigue
• Headache, lightheadedness, or mild gastrointestinal upset

Serious adverse effects (seek medical care)

• Liver problems: persistent abdominal pain, dark urine, yellowing of skin/eyes
• Thromboembolic events: leg swelling, chest pain, sudden shortness of breath
• Intracranial hypertension (pseudotumor cerebri): severe headache, visual changes
• Severe hypertension or cardiovascular symptoms
• Allergic reactions: hives, rash, swelling of face/lips/tongue, trouble breathing

Voice changes (deepening) and clitoral enlargement have been reported; some androgenic changes may be only partially reversible. Discuss risks with your clinician before starting therapy.

Reporting side effects

If you suspect an adverse reaction, contact your prescriber or pharmacist promptly. In the United States, you may also report side effects to FDA MedWatch (1‑800‑FDA‑1088) or online at the FDA MedWatch website.

Drug interactions with Danazol

Always tell your U.S.-licensed healthcare provider and pharmacist about every prescription, over-the-counter medicine, and supplement you take. Danazol has clinically relevant interactions, including:

• Anticoagulants (e.g., warfarin): danazol may potentiate anticoagulant effect; closer INR monitoring and dose adjustments may be necessary.
• Statins (especially simvastatin and lovastatin): increased risk of myopathy; clinicians often avoid this combination or choose alternatives.
• Calcineurin inhibitors (e.g., cyclosporine, tacrolimus): risk of increased levels and toxicity; monitoring and dose adjustments required.
• Antidiabetic agents (insulin or oral): androgenic activity may affect glycemic control; monitor blood glucose.
• CYP inhibitors/inducers (e.g., azole antifungals, macrolide antibiotics, certain anticonvulsants): may alter danazol plasma concentrations.
• Antihypertensives: androgenic effects may influence blood pressure; monitor closely.
• Concomitant hepatotoxic drugs: additive risk for liver injury; clinicians may avoid or monitor more frequently.

This list is not exhaustive. Maintain an up-to-date medication list and share it at every visit to reduce the risk of harmful interactions.

How to take Danazol safely

Follow your prescriber’s instructions exactly. Here are general, U.S.-oriented tips to support safe use:

• Take Danazol at consistent times each day. If it upsets your stomach, ask your clinician if taking it with food is appropriate.
• Do not skip lab monitoring. Periodic liver function and lipid tests help ensure ongoing safety.
• Use effective contraception if there is any possibility of pregnancy. Notify your prescriber immediately if you miss a period or suspect pregnancy.
• Avoid alcohol or limit intake based on your clinician’s guidance, particularly if liver enzymes are elevated.
• Report new or worsening headaches, vision changes, chest pain, or unusual swelling promptly.

Missed dose and overdose

If you miss a dose, take it as soon as you remember unless it is close to the next scheduled dose—if so, skip the missed dose. Do not double up. In case of suspected overdose, contact your clinician or call the Poison Help line at 1‑800‑222‑1222 in the United States.

Storage and handling

Store Danazol capsules at room temperature in a dry place, away from excess heat and moisture. Keep out of reach of children and pets. Do not use after the expiration date. Return unused or expired medication via pharmacy take-back programs where available.

Alternatives and comparative therapies

Depending on your diagnosis and medical history, alternatives to Danazol may include:

• Endometriosis: combined oral contraceptives, progestins (e.g., norethindrone), levonorgestrel IUD, GnRH agonists or antagonists with add-back therapy, aromatase inhibitors in select cases.
• Fibrocystic breast disease: lifestyle modifications, NSAIDs or acetaminophen for pain, hormonal options as guided by a clinician.
• Hereditary angioedema: C1-INH replacement therapies, kallikrein inhibitors, or bradykinin receptor antagonists for prophylaxis and/or on-demand treatment.

Your prescriber will help balance efficacy, side effects, long-term safety, and access considerations to choose the best regimen.

Insurance, shipping, and returns (U.S.)

Most U.S. insurance plans cover generic danazol when medically appropriate, though prior authorization may be required for certain indications. If your plan mandates step therapy, your clinician may need to document prior treatments or clinical rationale. Many pharmacies provide mail-order delivery to U.S. addresses; shipping times vary by location, stock, and carrier. Verify your pharmacy’s shipping options, signature requirements, and costs at checkout. For safety and regulatory reasons, pharmacies typically cannot accept returns of dispensed prescription medication; consult your pharmacy’s policy for specific details.

Frequently asked questions (FAQ)

Is Danazol available without a prescription in the U.S.?
No. Danazol is a prescription medication in the United States. A valid prescription from a U.S.-licensed clinician is required.

How long does it take to notice improvements?
It varies by condition. Some individuals report symptom relief within weeks, but optimal effects—especially for endometriosis—can take several months. Your clinician will reassess and adjust therapy as needed.

Will Danazol affect fertility?
Danazol suppresses ovulation while in use and is not recommended in those who are pregnant or trying to conceive. Discuss family planning with your clinician prior to starting therapy.

Can I drink alcohol while taking Danazol?
Alcohol can stress the liver. Ask your clinician for personalized guidance, especially if your liver enzymes are elevated.

What happens if I develop acne or hair changes?
These androgenic effects are relatively common and may improve after dose reduction or discontinuation. Alert your prescriber if these changes become bothersome.

Professional guidance and U.S. regulatory notice

Information on this page is educational and U.S.-focused. It does not replace the advice of your clinician or pharmacist. Danazol should be prescribed and monitored by a qualified U.S.-licensed healthcare professional, with attention to contraindications, contraception, lab monitoring, and potential interactions. Use only medications obtained from legitimate, U.S.-licensed pharmacies. If you have urgent symptoms (e.g., signs of liver injury, stroke, or blood clots), call 911 or seek emergency care immediately.

Ready to discuss Danazol with your clinician?

When your U.S.-licensed prescriber determines Danazol is appropriate for your condition, you can have your prescription filled at a licensed U.S. pharmacy and delivered discreetly to your address.

• Prescription required in the United States
• Licensed U.S. pharmacies with secure, trackable delivery
• Authentic medication from verified manufacturers
• Flexible strengths (50 mg, 100 mg, 200 mg) for individualized dosing
• Pharmacist support for counseling, interactions, and refills

Join patients across the U.S. who work with their clinicians to access Danazol safely and responsibly. If Danazol is right for you, your care team will help you get started and monitor progress throughout treatment.

Buy Danazol Now